Can I get laser lipo with protein s deficiency and do I need medical clearance from my PC?

You can have the treatment as long as it’s local anesthetic and not an excessive amount of treatment (i.e. multiple areas)  . There is no increase in clotting disorders when done with local, when general anesthesia is performed then there is an increased risk 

Dear DC,Protein c and s deficiency put you at risks for blood clots when you have procedures. I know many people who have had procedures with these conditions and have done fine, but you should take extra DVT precautions and early ambulation.Best. Dr BrechtSeattle, Wa

Hi and welcome to our forum!
Protein S deficiency is a rare condition, an autosomal dominant trait or secondary to Vitamin K deficiency. It results in increased risk of venous thrombosis and pulmonary embolism. Liposuction in and of itself has known complications of venous thrombosis and pulmonary embolism, especially if performed under general anesthesia. Your hematologist is required to make this difficult decision based upon relative risk. While most coagulopathies cause bleeding, this coagulopathy increases clotting. 
I would rather diet...
Best wishes