If a Vial of Unmixed Botox is Left at Room Temperature (Not Frozen) Can It Still Be Used?

Contact the Allergan company to find out. They  have a most wonderfully supportive and academic science department. How many hours is satisfactory to be left at room temperature before dilution and storage, or restorage after delivery.  The Botox is shipped on dry ice to protect it during transportation. It normally is unpacked and placed in a freezer before mixing with sterlie saline.

It is against Allergan's recommendations to use Botox that has not been stored at the appropriate temperature.  You run the risk of delivering a treatment that may not be effective.  While it is likely that it would be fine, if a patient that is paying for their product, you want to insure that it is efficacious.

Almost every office follows Allergan storage recommendations.  The product is so expensive, there is no reason to leave this to change.  However, it is clear that this product is actually much tougher that initially described by Allergan.  It is likely that product left out on the counter will be just find, even for multiple days.  Again, no office would be deviating from Allergan recommendations so the incentive to actually put this to the test does not exist.  It is worth noting that Xeomin a competing botulinum toxin product requires no refrigeration.