Molecular Amyloidosis - Options?

Question

I’ve had Mulecular Amyloidosis on my upper back since teenage years. This condition has highly impacted my self confidence. I have no freedom when it comes to buying dresses or swimsuits. I have to buy clothes that cover my back. This bothers me significantly and I am willing to go with the most expensive procedures ( if effective) to address this condition. I am tired of hearing that nothing works for this. Any suggestions or leads appreciated.

Anna Chacon, MD, FAAD · Answer

I'm sorry to hear about the impact that macular amyloidosis has had on your life. This condition can indeed be challenging to treat, but there are several options you might consider exploring, especially if you're open to various procedures. Here are some potential treatments:

Topical Treatments:

Corticosteroid Creams: May help reduce inflammation and itching.
Calcineurin Inhibitors: Such as tacrolimus or pimecrolimus, which can help manage symptoms by modulating the immune response.
Laser Therapy:

Fractional Laser Resurfacing: This can help improve skin texture and appearance by promoting collagen remodeling.
Q-switched Nd:YAG Laser: Has been used in some cases to reduce pigmentation and improve skin texture.
Dermabrasion: A mechanical exfoliation technique that can help improve skin texture by removing the top layers of skin.

Chemical Peels: These can help exfoliate the skin and potentially reduce pigmentation.

Phototherapy: Narrowband UVB phototherapy might help in some cases by reducing skin pigmentation and lesions.

Systemic Treatments:

Retinoids: Oral or topical retinoids may help in managing the condition by promoting skin cell turnover.
It's crucial to consult with a dermatologist who has experience in treating macular amyloidosis. They can evaluate your specific situation and recommend a treatment plan tailored to your needs. While it can be challenging to completely eliminate the condition, these treatments may help improve the appearance of your skin and enhance your confidence.

Molecular Amyloidosis - Options?

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Molecular Amyloidosis - Options?

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