Darolutamide for hair loss AGA: will the effectiveness of this agent fade after long-term use?

There aren't any long-term studies published on the long-term effectiveness of Darolutamide. I suggest seeing a hair loss expert now to evaluate and go over your condition and provide you information about your best treatment options. There are great non-invasive options like prp/progesterone and/or hair transplantation. See an expert. Best, Dr. Emer

Dorolutamide is in phase 3 studies for oral use in the United States. You are using a topical compound. I don't believe enough studies have been completed and patients have been treated to determine the characteristics of this particular anti-androgen for hair loss. Most of the other anti-androgens do not lose Effectiveness while a few become partially ineffective. I believe you should work with a hair loss expert.

Darolutamide is still a research drug with no formal approval. Its use in hair loss has not been studied given it’s restricted use. There is no good data to answer your question.