Botox for Frown Lines (52 Units) Doesn't Seem to Work. Why? (photo)

It is unusual that have not seen any improvement with 52 units of Botox. Many factors can affect the results, from the dilution, how long ago the vial was open, if has been properly stored, the site where it was injected. Also you need to aks if you really got Botox, or a different botulim toxin, like Dysport, Xeomin, etc.

Did you doctor take a picture of you at rest and frowning prior to your first injection?  This would be useful to compare.  If you have no effect whatsoever, then either the Botox was bad or you have an antibody.  It would be very unusual to not have complete effect from that much Botox.  I typically inject 15u for the frowners and it is plenty for the vast majority of patients.