One of my staff left out an undiluted bottle of Botox, and it was not refrigerated for about 3 days. Is it still effective?

The diversity of opinion among the RealSelf experts is interesting. My hunch is that Dr. Smith is the voice of reason.

I've had Botox arrive from Allergan at room temperature due to a shipping delay from inclement weather. The product worked fine. If you decide to use the product, save the bottle and check your patient in a week or so to ensure efficacy. If there's a problem with this vial, call Allergan with the lot number, and they would likely replace it at no charge. If you feel uncomfortable offering this to your patients, inject your staff, your family or yourself and let us know your experience.

Hope this helps.

Dr. Joseph

It would not seem prudent to use this product on a paying patient if even the slightest chance that it would be ineffective or sub par.  

When we have had similar situations, we have our staff use the product rather than risking an unhappy patient.  Keep in mind that, even if the patient is monitored and will be cared for in the event that the product was ineffective, his/her time is valuable and should not be subjected to another visit and potentially needless needle sticks.

 

 

Testing for the FDA of Botox's effectiveness and safety had been done under certain conditions.  Varying these conditions could change the outcome possibly, but this probably hasn't been studied.  You should check with Allergan's scientific team who will probably tell you to discard the bottle and not take a chance.  I have found their team to be very responsive!