Step one is proper oral hygiene (I always tell my patients whatever you have been doing up until starting invisalign for a fresh healthy mouth... double it). Second is to NEVER eat or drink with your aligners in place and try to brush or at minimum rinse with water after snacking and eating.Step three is to go to the OAPCLEANER website and get a 3 month supply. This cleaner works great.I have found, the best way to keep the aligners clean from bacteria, viruses and fungi is with the use of a product called OAP Cleaner. OAP provides instant cleaning of Invisalign and it takes only 60 seconds to use. The carefully formulated, proprietary cleaning solution is effective at cleaning and sanitizing all types of orthodontic appliances. It has clinically been shown to kill 99.99% of all viruses, bacteria, fungi and germs on contact. It also removes stains, plaque and offensive odors. The use of a brush to scrub and rid these critters and plaque off of your alignerstogether with OAP to sanitize and clean your aligner is the way to go.OAP is BPA, persulfate and chlorine-free, and is completely safe to use on Invisalign, as well as Invisalign storage containers. It is a gentle and mild cleaning agent that won’t cause discoloration of the plastic or result in abrasion of any surface material.