Silikon 1000 is approved on-label for retinal detachment in the eye. However, it can be used off-label for facial filling. In the hands of an expert injector with experience and proper technique, it is an excellent facial filler as it gives precise, permanent and natural-appearing results. We use it for aging rhytes of the face, acne scars, volume loss, facial lipoatrophy, surgical scars, aging hands, and aging lines in the neck. I have injected several hundred patients and my mentor and father has injected thousands of patients over 40 plus years. Neither one of us has ever had a patient have any serious complications or who developed granulomas.