Safe to Have Wine 3 Weeks After Tummy Tuck?

The reason for the concern about alcohol consumption after surgery is twofold: First is the potential interaction with pain medications, and second is that alcohol inhibits blood clotting so bleeding may be a concern. However you should be well on your way to healing and a glass of wine shouldn't be a problem.
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At this point in time, if your drains are out and there are no signs of seroma, it should be safe to consume alcohol in moderation without any significant concerns.
Your surgeon may feel ohterwise and it is best to consult with him/her prior to imbibing.