As of this writing, there is no medicine or cream to make breasts smaller. There are many very good surgical options. Please see a board certified plastic surgeon. Together you will review your goals and expectations and come up with a plan.
I do not know of a medicine or treatment that can accomplish this and it even makes sense that none exists - who would go through the surgery if there were a non-surgical treatment that is just as good?That being said, you may benefit from having one or more consultations with board-certified plastic surgeons who can go over the advantages and disadvantages of this surgery. Breast reduction patients are, in general, among the happiest of plastic surgery patients and you may feel differently once you've had a change to talk to an expert.I hope that this helps and good luck,Dr. Alan EnglerMember of RealSelf100