What Are the Effects of Using Juvederm over a Long Time?

Hyaluronic acid lip injections with Juvederm or Restylane have been shown to stimulate new collagen formation through mechanical stretching of the dermis which causes activation of dermal fibroblasts. This accounts for its longer lasting effect after the hyaluronic acid has been absorbed by your skin. This can be cumulative so the results can begin to last longer with repeated injections. This is only one of the many reasons why fillers like Juvederm are a much better option than the permanent treatments.

 Juvederm, like any filler, may cause some internal scarring, of the lip, or any tissue from repeated injection trauma.  I have augmented lips using fillers like Restylane and Juvederm for over 20 years and every once in awhile, if the lips appear to have scar tissue building up from repeated injections...have patients let everything go for 6-9 months until the lips soften again.

  As for lip implants, IMHO again of using Gore Tex, Silastic , fat transfer and Alloderm for over 20 years...Alloderm is the gold standard for lip implants IMHO.  Soft, supple an natural...Alloderm is my implant of choice for augmenting the lips.  Lip Implants can IMHO, reliably offer a degree of lip augmentation unattainable through lip injections using fillers.  

  It's important to understand that there's no inherent magic in any filler or implant but rather the magic must reside in the MD's ability to understand and follow the proper aesthetics of facial beauty (and lip proportion) for the creation of a naturally, more attractive face and in this case lips.