What Are the Effects of Using Juvederm over a Long Time?

Great question that was beautifully answered by Dr. Rueckl.  I don't have much more to add except  to mirror his warning about permanent implants in lips.  Juvederm is a safe, natural looking option.  Stick with it!

Many of my patients who get repeated juvederm or fillers to the lips often opt for lip implants to avoid having to get repeated injections.  My preferred lip implant is reversible, in that it can be removed at a later time if you choose to do so.  Please consult with a board certified specialist who can assist you in achieving the results you desire.

I do not think that the body absorbs Juvederm faster as you keep using the product. What may happen is that the body responds a bit with increased collagen production which may require less filler product over time.

Hyaluronic acid lip injections with Juvederm or Restylane have been shown to stimulate new collagen formation through mechanical stretching of the dermis which causes activation of dermal fibroblasts. This accounts for its longer lasting effect after the hyaluronic acid has been absorbed by your skin. This can be cumulative so the results can begin to last longer with repeated injections. This is only one of the many reasons why fillers like Juvederm are a much better option than the permanent treatments.

 Juvederm, like any filler, may cause some internal scarring, of the lip, or any tissue from repeated injection trauma.  I have augmented lips using fillers like Restylane and Juvederm for over 20 years and every once in awhile, if the lips appear to have scar tissue building up from repeated injections...have patients let everything go for 6-9 months until the lips soften again.

  As for lip implants, IMHO again of using Gore Tex, Silastic , fat transfer and Alloderm for over 20 years...Alloderm is the gold standard for lip implants IMHO.  Soft, supple an natural...Alloderm is my implant of choice for augmenting the lips.  Lip Implants can IMHO, reliably offer a degree of lip augmentation unattainable through lip injections using fillers.  

  It's important to understand that there's no inherent magic in any filler or implant but rather the magic must reside in the MD's ability to understand and follow the proper aesthetics of facial beauty (and lip proportion) for the creation of a naturally, more attractive face and in this case lips.