What Are the Effects of Using Juvederm over a Long Time?

If I have my lips injected with juvederm ultra xc every few months (as the product gradually wears out but not completely)over a lifetime, is it possible that it could gradually last longer? Or does the body grow more familiar to the product and with every treatment the body absorbs it faster than the last time? I really want to fix my lips permanently, but from what I've read about the permanent options so far, I'm wary of all of the side effects and dangers. Is juvederm long-term safe?

Doctor Answers 6

Long-term Juvederm vs permanent lip implants or injections

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With many HA fillers, re-injecting before you return to baseline is a good idea. For instance, the Restylane studies show that if you do this, it does actually get the product to last longer. They suggest that you get an injection, then another in 6 months, then another in 6 more months, and by way of "stacking" the product, you can actually get a better result and long-lasting filler than if you injected 3 syringes originally. The same would be true for Juvederm because it's also an HA filler. Juvederm and Restylane are extremely safe long-term.

I never recommend permanent fillers or implants. I have taken out so many problem ones over the years, I probably couldn't even begin to count. It seems like a good idea, until you realize that as your body ages naturally, your face, lips, etc. do change shape, even slightly, and putting something permanent in there does not allow the body to do this. While it would seem like a good idea, what actually happens is the body contorts around the permanent filler and people end up looking slightly deformed. It's much better to be able to adjust fillers and such as the body ages so you can fill different areas and spaces at different times.

Lip Augmentation

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Many of my patients who get repeated juvederm or fillers to the lips often opt for lip implants to avoid having to get repeated injections.  My preferred lip implant is reversible, in that it can be removed at a later time if you choose to do so.  Please consult with a board certified specialist who can assist you in achieving the results you desire.

Kimberly Lee, MD
Beverly Hills Facial Plastic Surgeon
5.0 out of 5 stars 13 reviews

Juvederm and effect on body

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I do not think that the body absorbs Juvederm faster as you keep using the product. What may happen is that the body responds a bit with increased collagen production which may require less filler product over time.

Steven Wallach, MD
New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

Long term use of Juvederm

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Hyaluronic acid lip injections with Juvederm or Restylane have been shown to stimulate new collagen formation through mechanical stretching of the dermis which causes activation of dermal fibroblasts. This accounts for its longer lasting effect after the hyaluronic acid has been absorbed by your skin. This can be cumulative so the results can begin to last longer with repeated injections. This is only one of the many reasons why fillers like Juvederm are a much better option than the permanent treatments.

Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
4.7 out of 5 stars 12 reviews

What Are the Effects of Using Juvederm over a Long Time?

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 Juvederm, like any filler, may cause some internal scarring, of the lip, or any tissue from repeated injection trauma.  I have augmented lips using fillers like Restylane and Juvederm for over 20 years and every once in awhile, if the lips appear to have scar tissue building up from repeated injections...have patients let everything go for 6-9 months until the lips soften again.

  As for lip implants, IMHO again of using Gore Tex, Silastic , fat transfer and Alloderm for over 20 years...Alloderm is the gold standard for lip implants IMHO.  Soft, supple an natural...Alloderm is my implant of choice for augmenting the lips.  Lip Implants can IMHO, reliably offer a degree of lip augmentation unattainable through lip injections using fillers.  

  It's important to understand that there's no inherent magic in any filler or implant but rather the magic must reside in the MD's ability to understand and follow the proper aesthetics of facial beauty (and lip proportion) for the creation of a naturally, more attractive face and in this case lips.  

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.7 out of 5 stars 28 reviews

Juvaderm long term

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Great question that was beautifully answered by Dr. Rueckl.  I don't have much more to add except  to mirror his warning about permanent implants in lips.  Juvederm is a safe, natural looking option.  Stick with it!

Jacqueline Calkin, MD
Sacramento Dermatologic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.