What is Cellenis and how does it compare to PRP? (photo)

Question

What’s the difference between cellenis and prp? I was told by a dr I should get cellenis under my eyes . I've done prp and prf injections in the past . I was wondering if Cellenis is any different and why is so expensive if it’s my own blood ?!! I didn’t like prp/ prf under my eyes because it didn’t last …! I was wondering if cellenis is better than nano fat ? Thanks

Jennifer R. Berman, MS, MD · Answer

1. PRP (Platelet-Rich Plasma):
What it is: PRP involves extracting your blood, centrifuging it to concentrate platelets, and injecting the plasma portion rich in growth factors.
Benefits: The growth factors promote collagen production and tissue repair.
Limitations: PRP results can be subtle and often require multiple sessions. The effects under the eyes are typically short-lived (a few months).
2. PRF (Platelet-Rich Fibrin):
What it is: PRF is a newer version of PRP, processed at a slower centrifugation speed without anticoagulants. This retains white blood cells and fibrin in addition to platelets.
Benefits: The fibrin matrix allows a slower release of growth factors over time, potentially leading to longer-lasting results than PRP.
Limitations: While improved, the longevity under the eyes can still be modest compared to more structural fillers or fat grafting.
3. Cellenis (Advanced PRP System):
What it is: Cellenis is a proprietary PRP system that optimizes platelet and growth factor concentration using specific centrifugation and filtering methods.
Why it's more expensive: The higher cost often reflects the advanced equipment, more rigorous protocols, and potentially higher concentration of active components compared to regular PRP.
Benefits: It may yield slightly better and longer-lasting results than standard PRP due to its enhanced preparation, but it’s still derived from your blood, so its longevity under the eyes might not differ dramatically from PRP/PRF.
4. Nanofat:
What it is: Nanofat involves harvesting your own fat (usually via liposuction), processing it into a very fine consistency, and injecting it into target areas. Unlike PRP or PRF, nanofat includes stem cells from adipose tissue.
Benefits:
Provides a structural volume boost (which PRP/PRF/Cellenis lack).
The stem cells can promote skin regeneration and improve texture over time.
Longevity: Nanofat typically lasts longer than PRP/PRF, often 1-2 years or more, because the fat provides a physical filler effect in addition to rejuvenation.
Comparing Cellenis and Nanofat:
Longevity: Nanofat is likely to last longer as it adds volume. Cellenis (like PRP) relies on growth factors, which may enhance skin quality but don’t add structural volume, so results fade quicker.
Suitability: If volume loss under your eyes is a concern, nanofat might be the better choice. If you’re mainly focused on skin texture and rejuvenation, Cellenis could be a good option.
Cost: While Cellenis is expensive, nanofat can also be costly due to the liposuction procedure and additional processing required.
Which is Best for You?
If PRP and PRF didn’t last long enough for you, it’s worth considering nanofat, as it offers both volume and regenerative benefits. Cellenis may offer some improvements, but if longevity is your primary goal, nanofat could be the better investment. Discuss with your doctor to weigh the benefits based on your specific needs and anatomy!

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