Can I combine DefenAge and Retin-a?

Question

I've been on a Retin-a regimen for many happy years but I want to try DefenAge. Can I add this to my regimen or do I need to stop Retin-a?

Rebecca Fitzgerald, MD · Answer

You can layer. Apply the retin-a as usual and then apply the DefenAge serum or products. The serum "seals" in the other products, so they are last applied (except sunscreen or makeup)

It's a novel product development and thus far we've have consistent positive feedback.

Monica Bonakdar, MD · Answer

The short answer is yes. But in truth you may not need to use both. 
A 2018 study compared the action of Defensin peptides which are the active ingredient in Defenage  against retinoic acid.  This study showed that Defenage rejuvenates facial skin similar to cosmetic retinoic acid, without the irritation.

Angelique M. Berens, MD · Answer

Hello,
It is okay to combine DefenAge and Retin-A!  You can apply Retin-A a couple minutes after applying the BioSerum (try to wait for the serum to dry).
Happy Skin!
Dr. Berens

Can I combine DefenAge and Retin-a?

Answers (3)

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