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DefenAge is a patent-pending, nonprescription skin-care technology system that claims to rejuvenate skin by reprogramming dormant cells to create new skin cells.
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You can trust RealSelf content to be unbiased and medically accurate. Learn more about our content standards.

You can trust RealSelf content to be unbiased and medically accurate. Learn more about our content standards.
I had a micro needling procedure and used DefenAge Products both before and after. The Step 1 was perfect to exfoliate prior to the micro needling. It prepared the skin to achieve maximum results. Following up with both Steps 2 and 3 completed the experience. I have been using DefenAge for three years now and...
Last year I had a lower face lift and documented the procedure here on RealSelf. I noticed how uneven my skin tone was and how bad my age spots were. My skin in my 40s is certainly nothing like it was 10 years ago. I decided to try DefenAge to help diminish my age spots and reduce my fine lines. It is suppose...


I started treatments in Oct of this year 2018 with CA skincare that when the Nurse Practitioner said I needed a better skin care regiment and suggested Defenage. It was the best advise. I turned 50 this past month and feel as if I look 40. Friends amd family noticed emmediate results and wanted to know what I...
Hello and thank you for your question! We absolutely love DefenAge in our practice for many reasons, one being that it truly is suitable for every patient. Yes, an olive-skinned person can use DefenAge skincare. The brand is known for its Age-Repair Defensins® technology, which promotes skin rejuvenation by activating dormant skin cells. DefenAge products are generally non-irritating, free from harsh retinoids, and suitable for all skin tones, including olive skin. However, here are a few ...
+1 answersIn the original studies results were documented with computerized imaging in 6 weeks. Skin dryness is normal at the beginning but subsides quickly. This occurs because the skin’s barrier is most likely damaged due to environmental exposure, stress, tobacco smoke, diet and ingredients in other skin care products. It may take up to 4 days to feel 24/7 Barrier Balance Cream’s deep moisture-repairing effects. This can be especially true if rich, creams were used previous to Defenage. The...
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