Does threading Radiesse work better than deep injections?

Most patients need a full syringe on each side of the face for a noticible improvement. Placing Radiesse deeper is usually recommended, although placement will depend on a number of factors that your provider will discuss with you.

Radiesse can work well with any technique.  It is not the "filler" per say it is the "filler" who is doing the injection that gives the best results.  I use Radiesse deep for lifting and contouring and more superficial for volume and shaping.