Is It Safe to Have Botox on Anti Depressants?

There is no contraindication to being on antidepressants and getting Botox injections. The medicines do not interact and you should be fine to have them.

There is no adverse chemical reaction between Botox and any FDA approved antidepressant.  Depression has a significant prevalence in the United States, as do hyperdynamic lines.  A patient on antidepressants can very safely have Botox without any greater risk of complication than baseline.