Is It Safe to Have Botox on Anti Depressants?

There should not be a contraindication against taking antidepressants when having Botox injected.  This class of medication is not on the list of those that should be avoided during Botox treatment.

Botulinum toxin has actually been shown to improve depression! 
Botulinum toxin was first isolated in the 20s, was first used therapeutically in 1968, and became approved in 1989 for eye issues. It has been used heavily for cosmetic use since 2002, and it was the first aesthetic drug ever approved.  All that is to say...it has a lot of safety data behind it. Recent evidence (coming out this week) proves that botulinum toxin does NOT enter your brain as it's distant cousin tetanus toxin does, which is where that theory came from. 
Botox, Dysport and Xeomin are the 3 botulinum toxins approved for cosmetic use in the US. They all work in the same way, at the presynaptic terminal blocking the release of acetylcholine - making the nerve temporarily unable to communicate with the muscle. It is broken down as a protein in our body with liver metabolism. Effects are temporary, and repeated use serves to take tension off of your skin, relaxing lines and wrinkles.
To ensure you are receiving the highest level of care, seek out a modernly trained, new-school dermatologic surgeon, oculoplastic surgeon, facial plastic surgeon or plastic surgeon who is board certified and fellowship trained in one of these "core four" cosmetic specialties. Membership in organizations like the American Academy of Facial Plastic and Reconstructive Surgery help to identify a highly trained surgeon.
Cameron Chesnut
#realself500 Physician

It IS safe to undergo Botox treatment while taking anti-depressants. As long as you have realistic expectations regarding the expected results of Botulinum toxin treatment, you're a good candidate.Stephen Weber MD, FACS

There is no contraindication to being on antidepressants and getting Botox injections. The medicines do not interact and you should be fine to have them.

There is no adverse chemical reaction between Botox and any FDA approved antidepressant.  Depression has a significant prevalence in the United States, as do hyperdynamic lines.  A patient on antidepressants can very safely have Botox without any greater risk of complication than baseline.

BOTOX is not a treatment for depression, not withstanding evidence that it does make people happier.  There is no evidence that there is an interaction.  You are not likely to have an issue having BOTOX while being on an anti-depressant.  However, please do disclose to your doctor all medications you are taking including the anit-depressant.

Emma,

There is no medical safety issue with Botox in someone taking antidepressants, but just be aware of other issues like whether you are emotionally prepared to try Botox, or if you have unrealistic expectations of what can be done with it. I encourage you to try it out. Interestingly, there have even been reports of a few patients saying they feel happier after Botox treatments--this effect is still being studied but is potentially promising.

Hello and thank you for the question.

There is no contraindication to undergo Botox Cosmetic Treatment if you are currently on antidepressants. Consult with you physician prior to treatment to make sure there are no underlying contraindications.

Kindest Regards, 

Glenn Vallecillos, M.D. F.A.C.S. 

Yes, there are no complications for Botox administered concurrently with antidepressants. However, any history of neurological diseases must be made known to your physician prior to treatment.

There is certainly no contra-indication to having Botox injected while one is taking anti-depressants. That said, you should always share with your doctor any and all medications you are taking (including vitamins and supplements and non-Western medications, such as Chinese medicine) during your first visit. On follow-up visits, you should let your physician know about any changes in your treatment regimen. This will help ensure higher quality care. Good luck! 

Dr. Chow in Arcadia, CA