PRF injections with no visible difference 6 weeks later. Should I continue?

Great question. PRF is a version of PRP. It has platelets and plasma like PRP, but also has a higher level of fibrin and white blood cells. It is usually done with other treatments (like filler), as it is not a singularly powerful intervention. Treatments are usually done about 6-8 weeks apart. There is not any good research/data that demonstrates its effectiveness at this time. PRF is NOT designed to improve volume (like filler), but is more designed to help improve SKIN quality. I would never offer PRF with the expectation of experiencing a dramatic result. Warm regards.

PRF typically requires 3–4 treatments spaced 4–6 weeks apart for noticeable results, and improvements are gradual, as it works by stimulating collagen and tissue regeneration. At 61, your body’s slower regenerative response might delay visible changes. If you want immediate volume or lifting, combination of different materials will be better option

PRF injections need time to work. Several monthly injections are suggested. If you want immediate resolutions of your wrinkles and folds you might want to consider Botox and fillers.