Why Wouldn't Wydase Work to Dissolve Juvederm?

Juvederm Plus takes at least 2-3 times as much hyaluronidase to dissolve it as other hyaluronic acid products, including Juvederm Ultra. If only a small amount of hyaluronidase was used each time, it may not have been enough.

By the way, while Botox can sometimes prevent wrinkles, fillers do not, they simple conceal them.

Dr. Kenneth Beer is an excellent cosmetic dermatologist in the Miami area.  Good luck. 

If the hyaluronidase did not
successfully break down the product, it is difficult to determine if this is
permanent or not. Generally, Juvederm Ultra Plus XC lasts for approximately
9-12 months, so I would recommend waiting at least this amount of time as it
may just take longer for your body to break the product down on its own.

Your Juvederm may have been injected too superficially. The Wydase will make the Juvederm disappear. You probably need more Wydase or it is not being placed in the right location.

   Hyaluronidase injected 4 times without any improvement may signal a granuloma that may not be as responsive to hyaluronidase.

If the lump is caused by Juvederm or another other hylauronic acid, then the Wydase will melt it.  It is possible that what you are observing is not from the Juvederm directly but possibly swelling from the injection, a small hematoma, an inflammatory reaction or something unrelated.  Are you sure it was Juvederm they injected and not Radiesse or other non-HA filler?

 

Good Luck.