Are there any brands of Retin-A better than others with regard to the effectiveness?
Retin-A Effectiveness Differ by Brands?
Doctor Answers 2
No Head to Head Studies as far As effectiveness
There are four branded tretinoin products: Retin A ( Ortho Derm); Atralin gel ( Coria); and Tretin-X ( Triax). There are a few generics out there that I know of including Altinac, Avita, and Tretinoin cream.
There are no effectiveness head to head studies I know of.
Atralin is a newer formulation. It contains hyaluronic acid and glycerin and has a slow delivery system to prevent irritation. Ortho also makes claims, which I believe, that their microsphere system offers a slower paced and more even delivery preventing irritation. I do think that Retin A by these two companies is much less irritating than its generic competitors. Tretin-X also has a modified delivery system to stymie ilrriation. In addition, they provide a foaming cleanser and a soothing moisturizer designed to be used with their tretinoin product.
If I were going to get the generic, I would chose either Avita or tretinoin cream by Spear. I prefer their formulations to other generics patients have brought in while crying about their facial irritation.