Does Restylane Increase Collagen Production?

Merely the process of injecting a needle without a filler will stimulate collagen growth, in fact there is a technique of making multiple punctures for skin rejuvenation based entirely on that. Some fillers are intended to be active stimulators of collagen growth, which would prolong the effect. The question then is how meaningful it is in terms of the clinical result. There are many advantages to HA fillers such as Restylane, but if collagen growth is the real goal there may be better ways to do it.

After multiple treatments, the placement itself of Restylane, not the product, may increase the body's production of collagen at the site of injecitons as a response to the healing of the needle insertions.

Thank you for your question. There is evidence that dermal filler injection, such as Restylane or Juvederm, does stimulate the body’s own production of collagen. However, this due to the stretching of the skin cells from the product. I hope this helps. Best of Luck!