Has anyone had any bad side effects from Restylane or from the anesthetic? What should I expect?

Restylane is a very well tolerated filler if applied correctly.  There may be minor bruising and swelling which may last 1-4 days after the injection and which are typically covered by makeup in the relatively unlikely instance they are noticeable.  Nodules and skin color changes are some of the more serious side effects but in the hands of an experienced practitioner, these issues are highly unlikely.  Of course over- or undercorrection can result in unwanted appearance.  Other side effects depend on the area applied, and special considerations need to be made for blood vessels, skin thickness, and lymphatics in the area.  Restylane around the eyes has a higher chance of untoward effects and must be applied with great care.  A thorough evaluation by an experienced practitioner is necessary to identify the best location for placement, the technique to place it, and the potential pitfalls of placement.

Like any fillers, there are side effects that can occur. I would advise you to schedule a consultation with a board certified expert injector for a detailed examination to discuss all possible treatment options and what your expectations are. 

Thank you for your question about Restylane side effects.
As with any HA filler injections, you can expect some short term side effects after Restylane Defyne injections.  The most common are bruising at the site of the injection and mild swelling over the areas treated.  Hyaluronic Acid Fillers, including Restylane Defyne are "hydrophilic" and attract and hold on to water, causing swelling.  This is typically mild and only lasts for a few days.  Your provider should also counsel you on post injection care.  This includes, but is not limited to, avoiding exercise for 24 hours, avoidance of aspirin/ibuprofen/fish oils to avoid bruising, avoiding heat or sun exposure for 24 hours, avoid waxing or laser treatments to the area for 24 hours, and avoiding massage of the injection site. 
 
To be sure, see two or more experienced, licensed and board-certified providers in your area for a complete evaluation to make sure you are a good candidate and that it is safe for you to have treatment.
I hope this helps.