Profound and Ultherapy are both FDA approved devices for facial rejuvenation. Their mechanism of action and anatomic targets are, however, quite different. Profound targets the skin, restoring hydration, elasticity and collagen content. I pioneered Profound's use to rejuvenate facial muscles including the forehead, eye and mouth regions.Ultherapy works deeper, in the facelift layer, stabilizing the face from below. There are three depths of action, the most superficial of which does also target the skin.I have used Profound since its release in 2015 and found that patient satisfaction is nearly 100%. I have had Ultherapy since 2011, shortly after its release, and have been very pleased with its use on the body, including breast, arms, abdomen, buttock and thighs.