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Can Spironolactone cause LPP hair loss? I have been on Spiro at high doses.

manggootOct 8, 2017
I have read that taking Spironolacton can induce a lichenoid reaction causing Lichen Planus but haven't found anything about it effecting Lichen Planopilaris. I have been on Spiro at high doses for a long time for AGA hair loss. Looking back when I tried to slowly replace Spironolactone with Androcur, I noticed some correlations lessening the dose / with less LPP symptoms but it is difficult to say for sure as there were many other drugs and Telogen Effluvium that may have been playing a part.

Answers (1)

From board-certified doctors and trusted medical professionals
Dr. Jeff Donovan, MD, PhD
Certified Dermatologist
Answered on Oct 9, 2017
Answer
1 person found this helpful

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You may have a scatricial alopecia type disorder. for example we can see both patch hair loss and eyebrow inflammation and hair loss in frontal fibrosing alopecia..So you may need to have a full exam with an hair surgeon, dermatologist and skin biopsy to find out reason for hair loss.

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It is not common but certainly possible. The chance of developing some side effects fo increase over time. See your presribing physician to sort out the presence or abscence of a link. 

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