Are There Long-Term Side Effects From Botox and is it Safe?

Can Botox have side effect in future?

Doctor Answers 18

Botulinum toxin safety

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Botulinum toxin was first isolated in the 20s, was first used therapeutically in 1968, and became approved in 1989 for eye issues. It has been used heavily for cosmetic use since 2002, and it was the first aesthetic drug ever approved.  All that is to has a lot of safety data behind it. Recent evidence (coming out this week) proves that botulinum toxin does NOT enter your brain as it's distant cousin tetanus toxin does, which is where that theory came from. 

Botox, Dysport and Xeomin are the 3 botulinum toxins approved for cosmetic use in the US. They all work in the same way, at the presynaptic terminal blocking the release of acetylcholine - making the nerve temporarily unable to communicate with the muscle. It is broken down as a protein in our body with liver metabolism. Effects are temporary, and repeated use serves to take tension off of your skin, relaxing lines and wrinkles.

To ensure you are receiving the highest level of care, seek out a modernly trained, new-school dermatologic surgeon, oculoplastic surgeon, facial plastic surgeon or plastic surgeon who is board certified and fellowship trained in one of these "core four" cosmetic specialties. Membership in organizations like the American Academy of Facial Plastic and Reconstructive Surgery help to identify a highly trained surgeon.

Cameron Chesnut

#realself500 Physician

Spokane Dermatologic Surgeon
4.9 out of 5 stars 123 reviews

Are There Long-Term Side Effects From Botox and is it Safe?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
It's impossible to predict what the answer will be in another 15-20 years but our experience so far has suggested that Botox is safe short- and long-term. On a related note, Botox for wrinkles uses a much smaller dose than patients receive for muscle spasticity. Those patients who've been receiving large doses of Botox for other functional problems also have not had problems further supporting our finding that cosmetic Botox is safe.

I hope this information is helpful.

Stephen Weber MD, FACS
Denver Facial Plastic Surgeon

Are anti-wrinkle treatments safe?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

The product has been used safely in medical treatments for over 30 years including in children at high doses for the treatment of spasticity in cerebral palsy and for spasms of the eyelid and neck muscles spasms. The doses used for cosmetic purposes are very low and with millions of patient treatments each year it has a proven safety track record with no long term side effects to cosmetic doses of this product.

Eddy Dona, MBBS, FRACS
Sydney Plastic Surgeon
5.0 out of 5 stars 96 reviews

You might also like...

Is Botox safe?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Is Botox safe? 

Botox is used for a variety of cosmetic and non-cosmetic purposes and has been safely used since the early 1990's. In 2002 the FDA approved it for use of frown lines. There have been many clinical trials and over 400 peer-reviewed articles in scientific and medical journals about it's use. Though rare, there can be serous side effects. Some people with certain medical conditions should not use Botox. Additionally, some individuals on certain medications should not have this procedure in case it leads to a drug interaction. It is important to disclose your full medical history and provide a list of medication to your doctor before he begins the procedure.

Francis X. Fleming, MD
Kennewick Plastic Surgeon
4.5 out of 5 stars 18 reviews

Botox and Safety

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

I have been using Botox for almost 20 years and have found it to be safe and effective.  There have been no long term side effects noted for Botox.  Most patients who receive Botox for cosmetic indications receive small amounts and have the injections repeated twice a year.  The continued rise in popularity of Botox shows how easy, safe, and effective Botox is.  For the best results please consult a board certified dermatologist for the best cosmetic results.

Long-Term Effects of Botox?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
When administered by an expert medical professional, Botox and all of the neuromodulators like Dysport and Xeomin have been proven to be very safe and effective. Studies have not shown any damaging long-term side effects from Botox. In fact, we were part of a 10 year Botox study proving that twice yearly treatments were not only safe and effectiuve but maintained a youthful appearance over time. To ensure the best results, it is necessary to visit an experienced injector. At my practice in San Diego, we house five of the most world-renowned injectable experts.

Mitchel P. Goldman, MD
San Diego Dermatologic Surgeon
4.9 out of 5 stars 26 reviews

Long Term Effects of Botox

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
I have been using Botox (Botulinum Toxin) to my patients for more than 20 years bu tI have not encountered any long term side effects except for atrophy of the frontalis muscle which may result in more prominent bony contour of the forehead. This is however not a problem in most patients and is extremely safe under the hands of a professional injector. 

Somyos Kunachak, MD
Thailand Facial Plastic Surgeon
4.7 out of 5 stars 17 reviews

Long Term side Effects from Botox and is it Safe

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
Botox has been used for over 20 years and thus far there have been no long term side effects. It is used in such small doses for wrinkles and for so long now that you should feel confident of no long term side effects.

Esta Kronberg, MD
Houston Dermatologic Surgeon
4.9 out of 5 stars 28 reviews

Botox safety

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
Botox and its competitors have been used for over 20 years with a great safety profile in properly trained hands. In my opinion properly trained hands mean a board certified dermatologist, plastic surgeon, facial plastic surgeon or oculoplastic surgeon.

Omar Ibrahimi, MD, PhD
Stamford Dermatologic Surgeon
4.9 out of 5 stars 28 reviews

Long-term Botox effects

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}
Botox has been used for several decades now, and no evidence of meaningful long-term side-effects have been noticed thus far.

William Numa, MD, FACS
Boston Facial Plastic Surgeon
5.0 out of 5 stars 7 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.