I had great results when I first started using Latisse, but that "honeymoon phase" only lasted 6-9 months; thereafter I would lose a large number of lashes at once. They would grow back, but never as thick as before. My prescribing doctor suggested that because it regulates the growth cycle of lashes, using it had put them all onto the same schedule, causing more to fall out at the same time. She suggested taking a week off every so often to "reset" the clock. Are you aware of this phenomenon?