This is an excellent question, and I’m glad you’re approaching it thoughtfully rather than assuming that a treatment that worked years ago will necessarily work the same way now. The short answer is: Sculptra can still be effective at age 80, and the fact that you remember it improving your cheek fullness in the past is actually an encouraging sign. Age alone does not make someone “too old” for Sculptra. What changes with age is how much improvement we can realistically expect and how we use the product. What Sculptra does best Sculptra is a collagen-stimulating injectable made of poly-L-lactic acid. Unlike hyaluronic acid fillers, it does not provide immediate volume correction. Instead, it works gradually by stimulating your body to produce new collagen over several months. It tends to be most helpful for: Hollow or flattened cheeks Loss of facial fullness Softening folds caused by volume loss Improving skin thickness and quality over time What it is less effective for Sculptra is not ideal for directly correcting individual lower-face wrinkles, especially: deep marionette lines, etched vertical lines around the mouth, or significant jowling caused by skin laxity and tissue descent. Those concerns are often caused by a combination of volume loss, skin laxity, and gravity, so restoring cheek support may improve them indirectly, but it usually will not erase them completely. At age 80, what I would expect The key question is whether you still have enough collagen-producing capacity for the treatment to be worthwhile. In my experience, many healthy patients in their late 70s and 80s do respond to Sculptra, although the response may be: slower, more subtle, and may require more than one treatment session to achieve a noticeable effect. Because facial aging at 80 is often accompanied by significant fat loss and bone remodeling, Sculptra is frequently better for creating overall facial softening and support rather than dramatic lifting. The fact that it helped you before matters Your prior experience is one of the most useful pieces of information. If you previously had visible improvement in cheek fullness, that suggests you were likely a good responder to collagen stimulation. While the response may not be identical now, it makes me more optimistic than I would be in someone who had never benefited from it. A realistic way to think about it If your goals are: “I want my cheeks to look fuller and less hollow” → Sculptra may be a very reasonable option. “I want the lower-face wrinkles and sagging to disappear” → Sculptra alone is unlikely to achieve that fully. For many patients your age, the most natural-looking approach is often a combination strategy, such as: Sculptra for cheek and temple support A small amount of hyaluronic acid filler for specific folds or marionette lines if needed Possibly skin resurfacing or biostimulatory treatments if skin texture is also a concern. My professional opinion Based on what you’ve shared, I would not dismiss Sculptra as ineffective simply because you are 80. In fact, for an 80-year-old who is primarily concerned about loss of cheek fullness, it can still be one of the more elegant and natural-looking options because it restores soft tissue support gradually rather than creating an overfilled appearance. I would go into treatment with the expectation of: moderate improvement in cheek fullness, some softening of lower-face folds due to improved support, and a result that develops gradually over 2–6 months, rather than immediate wrinkle correction. So, in your situation, I do think Sculptra could still be worthwhile, particularly for cheek volume restoration, but I would view it as a treatment for overall facial rejuvenation and fullness rather than as a reliable standalone solution for all lower-face wrinkles and laxity.