You can use Cosmelan if you have sensitive skin, but I would encourage you to do so only under the care of a physician. We have many patients with very sensitive skin who use Cosmelan but there are things we alter in the steps to alleviate irritation and redness for those with extremely sensitive skin. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."