Does Spironolactone cause weight gain?

Question

my doctor put me on 25 mg of Spironolactone twice daily to help hormonal acne. I was researching reviews online and many women have said it caused weight gain and cellulite, and that you can have a bad breakout when you first start on it. my Doctor said most his patients started seeing results within three weeks and did not experience I intial breakouts. Wanted to know why and if Spironolactone can cause these reactions. Is cellulite because it effect estrogen levels? I'm nervous to start it

Douglas Taranow, DO, FACOS · Answer

There is no proof that Spironolactone can cause weight gain, I've heard more patients say they have lost weight on it due to the fact it is a diuretic, which would cause less bloating. As for the amount of time it takes to start working, that's case by case, but its generally after one month,  you're also on a low dosage of the medication so I would assume the side effects will be minimal. You should discuss potassium intake with your doctor while on this medicine, too much potassium could be dangerous which should be your biggest concern.

Does Spironolactone cause weight gain?

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