Botox doesn’t seem to erase my glabellar crease - What will? (photo)

Expressive glabellar lines may have some static component to them. This component unfortunately cannot be corrected with Botox. I would continue with Botox injections since they at least improve the appearance of your glabellar lines and it will also prevent them from getting worse in the future. I don’t recommend fillers in this situation because of the risks associated with injections in this area.

Great question! Botox is fantastic for preventing movement-based wrinkles, but when a crease is deeply etched into the skin, it becomes a static wrinkle—which means Botox alone won’t fully erase it.
Why? Botox relaxes the muscle, but if the line is still visible at rest, it’s due to collagen loss and repetitive folding over time.
Dermal Filler (RHA, Juvederm, or Belotero) - A tiny amount of soft, flexible filler can plump the crease to smooth it out while maintaining a natural look. When done correctly, it’s safe and effective.
RF Microneedling or Resurfacing Treatments - Boosts collagen and skin remodeling over time to soften the crease naturally.
Smooth PDO Threads → Can help lift and tighten the skin while encouraging collagen growth.
I understand concerns about filler, especially in this high-risk area. The key is seeing an experienced injector who understands safe techniques—like using a cannula for precision and minimizing vascular risk. I personally use the least amount necessary for a subtle, natural result.

Well unfortunately you are blessed with very strong corrugator muscles between your brows. Botox (or any of the other neurotoxins) should help considerably, but may not get rid of the line completely. I do not recommend filler in this area. RF microneedling may help some (Virtue, Morpheus, etc). Hope that helps!