Hello and thank you for your question! Yes, certain areas of the body tend to be more responsive to CoolSculpting than others. CoolSculpting works best in areas with pinchable fat, as it targets subcutaneous fat (the fat just under the skin) rather than visceral fat (which surrounds organs). Additionally, CoolSculpt Elite achieves much better results than the original CoolSculpt machine. Areas that respond well: Abdomen (belly fat) – One of the most popular areas, as it tends to have a good amount of subcutaneous fat, making it responsive to treatment. Flanks (love handles) – Usually highly responsive, providing noticeable contouring with treatment. Thighs (inner and outer) – Both areas generally respond well, especially the outer thighs (saddlebags) where fat is more localized. Double chin (submental area) – This small area often shows good results after a few sessions. Back fat (upper and lower) – Typically shows good improvement as the fat in this area is more pinchable. Bra fat (around the bra line) – Another pinchable fat area that often responds well. Areas that may be less responsive: Upper arms – The fat in this area can be more fibrous and dense, which might make it less responsive compared to other areas. Lower legs (calves) – This area is less commonly treated because it often has less subcutaneous fat and might not respond as well. Areas with more fibrous or firm fat – Areas where fat is more fibrous, like in individuals with dense muscle mass or previous surgery scars, may show slower or less dramatic results. Results can vary based on factors like the thickness of fat, your body composition, and your skin’s elasticity. Multiple treatments may be needed to achieve the desired results in less responsive areas. I hope this helps! Genie Alexander, RN BSN for Anna Petropoulos, MD FRCS at Center for Classic Beauty, Boston & Danvers MA.