Can I use Retin-A to treat the lines/wrinkles on my lips?

If you are talking about the red body of your lips, fillers can help smooth the lines and then regular moisturizers and sunscreen can be used to help to protect and maintain the improvement. Retin A may be too drying and irritating for direct use on the lips. If by any chance, you are also suffering from vertical lipstick bleeding (aka "smoker's" or "bar code") lines around the mouth--a very common, age-related problem resulting most often from years of repetitive, daily use of the expression lines around the mouth and from the permanent surface "etching" and creasing resulting from those movements. Chronic overexposure to the sun and smoking can both speed the develop of and worsen these lines.To best treat these lines, microdroplets of Botox (or Dysport or Xeomin) may be used to diminish the dynamic (expression muscle-related) component underlying their development and fillers, such as Belotero Balance (my go-to for this in my Upper East Side Manhattan practice) or Teosyal Redensity II (my choice in my Israel satellite facility, where a far greater number of regulatory agency approved fillers are available), can elevate and smooth the existing creases and etch markings. For maintenance of the improvement achieved through the above and for prevention of continuing damage, smoking cessation (if applicable) and regular sunscreen use are of course essential, as are the regular use of at-home prescription strength agents like Retin A (or other retinoids) and alpha hydroxyacids (like glycolic acid) would be helpful. Happy holidays and best of luck to you.