Deep/etched wrinkle still present after Botox (Photo)

Hello and thank you for your question. It is always best to see you face to face for a consult and examination however in this case it sounds as though you have tried a lot of options. One that you haven't is a very fine skin booster injected very superficially in the line helping lift it directly and hopefully give you a smoother result. I hope that helps answer your question. Always seek an experienced and qualified medical professional for these treatments. Very best wishes

at home peels like cosmelan, enlighten and aerify along with dermarolling (EmerageSkin roller with anteage AERIFY MD ampules weekly, see link) should be started now to prevent further aging. in office you need more than MNRF, everyone should be getting laser every 3-4 months, botox every 2-3 months ,and peels monthly with facials. botox doesnt get rid of all lines it prevents them from coming long term.

For facial rejuvenation, I would suggest a combination approach of
1) skin care with products and PRP/microneedling
2) PDT light therapy few times a month with growth factors
3) laser treatments like clear and brilliant regularly and a few times a year Fraxel/halo Viva, Co2/Erbium
4) Sculptra injections a few times a year for collagen production with fillers like juvederm/restylane/belotero/radiesse/bellafill
5) thermage/ultherapy for yearly skin tightening with or without PDO or cone based instalift threads for lifting
6) botox every 2-3 months to stop movement lines and prevent lines at rest
7) deep microneedling RF like Fractora/morpheus8 for tightening of the skin
8) Vascular laser like vbeam/excel V or BBL forever young treatment every quarter (3-4 months)

Best, Dr. Emer.