DAO Botox targets the depressor anguli oris (DAO) muscles, which pull the corners of the mouth downward. When these muscles are overly active, they can contribute to a downturned-mouth appearance, sometimes making the face look sad, tired, or stern even when you're feeling completely fine. By relaxing these muscles, Botox may help: Lift the corners of the mouth slightly, creating a more neutral or subtly upturned appearance. Soften a downturned expression, especially when it is caused by muscle activity. Improve facial balance by reducing the downward pull around the mouth. However, DAO Botox does not directly treat lower-face skin laxity, jowls, or significant sagging. If the concern is loose skin, loss of facial volume, or changes in the jawline, relaxing the DAO muscles alone is unlikely to produce a noticeable lifting effect. Other treatments may be more appropriate depending on the underlying cause. It's also important to have the area assessed by an experienced injector, since excessive or poorly placed Botox around the mouth can affect smiling, speech, or lower-lip movement. Overall, DAO Botox can be a nice, subtle treatment for a downturned mouth, but it is not a substitute for a true lower-face tightening or lifting procedure.