Taking a 3mg dose of low-dose naltrexone 60 hours before your lip filler appointment is generally unlikely to cause significant issues with bruising or swelling. Naltrexone is not an anti-inflammatory, and its effects on bleeding or bruising are minimal compared to other medications like NSAIDs or blood thinners. However, if you have any concerns, it's always best to discuss them with your healthcare provider or the practitioner performing the procedure. Here are some additional tips to help minimize bruising and swelling: Avoid Certain Substances: In the days leading up to your appointment, avoid other substances that can increase the risk of bruising, such as alcohol, aspirin, and herbal supplements like fish oil, vitamin E, ginkgo biloba, and garlic. Apply Arnica: Consider using arnica cream or tablets before and after your procedure, as they may help reduce bruising and swelling. Use Cold Compresses: After the procedure, applying a cold compress to the area can help reduce swelling and minimize bruising. Stay Hydrated and Eat Healthily: Maintaining good hydration and consuming a diet rich in fruits and vegetables can support your body’s healing processes. Follow Post-Procedure Instructions: Adhere closely to any aftercare instructions provided by your practitioner to ensure optimal healing and results. If you’re still concerned, reach out to your injector for personalized advice based on your medical history and the specifics of your upcoming procedure.