My Skin is Extremely Sensitive and Dry After Accutane Course. How Long Will This Last?

Accutane is a go-to medication for patients with recalcitrant cystic acne. It can reduce pore size and also reduce sebum production in your skin, making it less oily; and in turn, dryer. Accutane can be used to control acne, but patients receiving the medication should be carefully monitored. In terms of skincare, always wear an appropriate sunscreen and reduce direct sun exposure. In my patients, I recommend a good ceramide moisturizer such as Elevase whenever they are on Accutane. This will keep the skin hydrated and reduce the oiliness of the skin that is associated with oil-based moisturizers.

Best,
Dr. Karamanoukian
Realself100 Surgeon

One of the ways Accutane works for Acne is by decreasing sebum (oil) production.  There is some permanent level of oil reduction but your oil production will ramp up again in 6-12 months.  Mind you, 20 mg per day for 3 months does not sound like an adequate course for acne so if you are expecting a permanent improvement in your acne you may be disappointed.  The wrinkles you are seeing are simply because your skin is drier and will disappear once you find a skin care regimen with the proper amount of moisture for your new skin.  Accutane has been shown in studies to reverse wrinkles in patients because of its retinol like effects so don't worry that you have done anything to prematurely age your skin.