Does Xeomin still take a few days till up to a week to take effect like Botox does?

I tried Xeomin for the first time instead of Botox and still see wrinkles buts its only been one day. How long till I see results?

Doctor Answers 10

Patience is a virtue

Xeomin, although newer to the United States, and less popular than other neurotoxins, is actually very widely used in the rest of the world.  The active core molecule resembles that of Botox, athough unlike Botox, does not need the additional protein complexes surrounding it.  From a pure chemistry point of view, this is an over-simplification, but is practically rather accurate.  The onset of action and duration of treatment, as well as the dosing and placement, is officially the same between the two.  Some people will note that the Xeomin-effect starts earlier than Botox. Incidentally, the average duration to maximal effect of Botox is 10-14 days, not generally seven.  

Both products are quoted as lasting three-to four months.

Vancouver Physician

Xeomin results

Yes Xeomin can take a up to 2 weeks before you will see all of the effects like Botox. One day is not enough time to see all the results but you should be seeing results shortly around 4-5 days. The full effect should be seen around the 2 weeks.

Edward E. Dickerson, IV, MD
Fayetteville Facial Plastic Surgeon
4.7 out of 5 stars 106 reviews

How long does Xeomin take to kick in?

Since the active ingredient of Xeomin and Botox are the same, the mechanism of action, duration to see results and duration of action are the same. I really like Xeomin.

Omeed Memar, MD, PhD
Chicago Dermatologic Surgeon
4.9 out of 5 stars 32 reviews


It typically takes 4-5 days before Neuromodulators begin to work and 2-3 weeks for their full effect to be seen. You should start seeing results shortly.

Xeomin and Botox- 2 weeks to see full results


Xeomin and Botox typically results are seen in the first week. Both products can take up to 2 weeks to see the full effect . Best, Dr Faraz

Time Of Onset For Xeomin After Injection

One day is too short a time frame for you to witness any effect from your xeomin injection.  Typically, patients begin to see the initial effects of xeomin approximately 3 days after injection, although the full effect of the injection may not be apparent for almost two weeks.  The duration of effect of xeomin is typically three to four months. In all of these parameters, xeomin performs almost identically to botox. 

Peter Lee, MD, FACS
Los Angeles Plastic Surgeon
4.6 out of 5 stars 47 reviews

Xeomin vs. Botox

Xeomin and Botox share the same active ingredient, botulinum type A, and are virtually interchangeable. The main difference between the two is the protein additive that exists in the Botox formula, which a very small percentage of patients can build a resistance to over time. Because of this, I sometimes recommend patients try Xeomin if they feel the effects of Botox do not last as long for them, or have ceased to take effect at all.

In regards to when Xeomin will begin to take effect, or how long it lasts, it is typically the same as Botox. You should begin to see the effects of Xeomin after about three days, and it may take up to two weeks for full results. The results of Xeomin should last you about 3-4 months, the same as Botox. 

Nissan Pilest, MD
Irvine Dermatologic Surgeon
4.7 out of 5 stars 17 reviews

1-2 Weeks

Xeomin, similarly to Botox, can take up to two weeks for full results. You should begin to see improvements 3-5 days after your treatment.

Patricia DePoli, MD, FACS
Skokie Plastic Surgeon
5.0 out of 5 stars 5 reviews

How long for Xeomin to work?

I would wait 1-2 weeks to see the full effect from a Xeomin treatment.  You most likely would begin to see some improvement before that time period, but the result should improve over more time.  It would be unusual to see any change after only one day.  

Michael I. Echavez, MD
San Francisco Facial Plastic Surgeon
4.5 out of 5 stars 18 reviews

Xeomin and Botox compared

Like Botox, Xeomin usually takes about 4 to 5 days to work, so just be patient. Results last about 4 months.

Harrison C. Putman III, MD
Peoria Facial Plastic Surgeon
4.7 out of 5 stars 13 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.