Is there any evidence that regular, long-term use of sleep medications such as Lunesta and Ambien can cause hair loss?

In  my opinion, side effects during clinical trials as well as post-marketing review failed to demonstrate hair loss with Lunesta or Ambien. However, various hair blogs have individuals who have reported these side effects. I would work with your physician who has prescribed the drug. Switch to an alternative for 3 to 6 months and reevaluate.PRP hair MD.com

Lunesta and Ambien should not, by itself cause hair loss but the warnings in some hair forums that suggest that there is an association should be noted.