2016 I had a skin test done to see if I would react to Juvederm Ultra XC. No reaction occurred but on the day we were set to inject the injector switched to Juvederm Ultra *Plus* XC. Immediately I had what seemed like an allergic reaction. My lips swelled quadruple their size. I was given antihistamine and they slowly started to shrink back. I've had successful lip injections since with a different brand and no nurse has seen this happen. I've had lidocaine in oral surgery w/ no issue.