Does terbinafine cause wrinkles or affect scar healing?

Question

I read that it decreases collagen production and reverses cutaneous fibrotic lesions, so would this mean it would affect your skin too? I’m taking it for toenail fungus. https://pubmed.ncbi.nlm.nih.gov/9894250/

Anna Chacon, MD, FAAD · Answer

Terbinafine is an antifungal medication commonly used to treat fungal infections such as toenail fungus. The study you referenced suggests that terbinafine can decrease collagen production in the context of treating fibrotic skin conditions, which are characterized by excessive collagen deposition.

However, the effects of terbinafine on collagen production and scar healing in healthy skin are not well-established. In general, the risk of terbinafine affecting normal skin functions such as wrinkle formation or scar healing is considered low, especially when used for a limited duration to treat toenail fungus. Most of the concerns regarding collagen and fibrotic lesions are specific to the pathological conditions being treated rather than normal skin physiology.

If you have specific concerns about how terbinafine might affect your skin, it would be best to discuss them with your dermatologist. They can provide personalized advice based on your medical history and the duration of your treatment.

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