Is it safe to have fine needle biopsy on a silicone filled cyst? Recently had explant implant was leaking silicone.

My recommendation would be to remove the silicone filled cyst.  Contact the PS who performed your implantation surgery to determine if the implants have a warranty, which will defray costs.  Most implant companies warranty breast implants for 10 years.
Kenneth Hughes, MD, Board Certified Plastic Surgeon
Los Angeles, CA

It is a very bad idea to aspirate any silicone from the breast as it is very thick and does not aspirate and may get into the blood stream where it can spread and clog arteries.  If you have retained silicone in the breast, you need a breast and chest wall clean out, including removal of any axillary silicone laden lymph nodes as well as detoxification and treatment of any co infections such as yeast which cause fatigue, muscle aches and mental clouding.  Peer reviewed literature has linked fibromyalgia and other adjuvant disease to silicone but most plastic surgeons have not read this literature.