Why can't Kybella be used wider out on the neck? Why can it only be used right under the chin?

Doctor Answers 19

Kybella is only FDA approved for the submental area

Kybella is approved for the submental region and can be used very safely in this area. Going higher along the jawline has shown in the initial clinical trials to produce occasional nerve injury that was temporary. Use caution and make sure you are going to a skilled injector. 

Washington DC Facial Plastic Surgeon
5.0 out of 5 stars 29 reviews

Why can't Kybella be used wider out on the neck? Why can it only be used right under the chin?

Thank you for your excellent question.  Kybella has been used in off label manners to address bra fat and other smaller areas of localized adiposity.  The only FDA indication for Kybella use is in the submental (below the chin) region and it is not recommended to be used wider for concerns of a temporary injury to the nerve responsible for controlling your lower lip. Hope this helps.

Nelson Castillo, MD
Atlanta Plastic Surgeon
5.0 out of 5 stars 38 reviews

Kybella and lateral neck

Early studies demonstrated risk to branches of the facial nerve, either from the injection or the inflammatory response, when injected in the lateral neck. Consequently, and treatment of the lateral neck would be considered "off label."   Note that patients that have global adipose deposits in the neck often get more benefit from alternative treatments such as liposuction or a formal neck lift.  Best of luck. 

Larry Lickstein, MD
Fairfax Plastic Surgeon
4.3 out of 5 stars 38 reviews

Why can't Kybella be used wider out on the neck? Why can it only be used right under the chin?

Kybella is FDA-approved for the fat under the chin (submental fat).  It can be used off-label further out to the sides of the neck when needed.  If you think you need Kybella further out to the sides of your neck, please make sure you are being treated to an expert injector.  Good luck!

Kybella can be used in a wider area if indicated

If the pocket of fat under your chin extends to a wider margin, Kybella is still effective and can be used.  I've also had success using Kybella off-label in other small areas of fat such as bra fat, back fat, and lipomas.
Good luck!

Daniel Levy, MD
Bellevue Dermatologic Surgeon
4.8 out of 5 stars 40 reviews

Kybella use

Kybella is a relatively new treatment used to address the double chin, also known as submental fullness. Thus far the FDA has only approved Kybella for treatment in this area. This is because the studies have only been performed in this area and the safety is established. Kybella has not been studied in the United States in other areas of the body so we do not know about risks and side effects. For this reason, use of Kybella in other areas is considered off label. Studies are in progress to determine the safety and efficacy of Kybella and other injectable treatments elsewhere on the body. A number of non-surgical body contouring treatment options are available such as Cool Sculpting and SculpSure. I recommend consulting with a doctor in your area for more information. Good luck!

Alex Eshaghian, MD, PhD
Encino Physician
5.0 out of 5 stars 1 review

Kybella: Best used for Double Chins for Permanent Fat Reduction

Wouldn't that be great if
Kybella could be used to treat other areas of subcutaneous fat in unwanted

At this time, however, Kybella is indicated ONLY for submental chin fat. The
safety and effectiveness of treating in other areas has not yet been studied.

Ronald Moser, MD
San Juan Capistrano Physician
5.0 out of 5 stars 1 review

Why can't Kybella be used to treat a wider area under the chin?

This is a matter of safety. Kybella is only FDA-approved to treat fat under the chin. Both CoolMini and Kybella are safe to be used under the chin. The jowls are best avoided. There may be increased risk of facial nerve injury when one treats a wider area. It is best to be seen by an experienced doctor to determine which treatment is best for you.

Douglas J. Key, MD
Portland Dermatologic Surgeon
4.5 out of 5 stars 15 reviews

Kybella outside the chin

Kybella is approved for the reduction of fat under the chin.  However, Kybella can theoretically be used anywhere there is excess fat.  However, it is usually cost-prohibitive and not predictable to use in larger areas.  Kybella has been used in the lateral fat of the neck as well as pre-bra fat with good success.  However, in off-label use, it should only be used by the most experienced of injectors due to increase risk.

Kyle Coleman, MD
New Orleans Dermatologic Surgeon
5.0 out of 5 stars 7 reviews


Thank you for your question. Kybella can be used "off label" on other areas, such as a wider area of the neck. The best advice is consult with your provider to determine if the areas are safe that you are wanting treated and if you are a good candidate for Kybella. Hope this helps! Dr Faraz

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.