Thank you for this excellent question. I am excited that we have both on the market now and I expect many patients using one or both treatment modalities. The Coolsculpting mini will get a broad reduction of the submental fat but has a little more difficult to customize the procedure as there is only one applicator size. Kybella allow for a customized treatment for every patient based on their physical exam. I would visit a plastic surgery a practice that offer both of these and who can also discuss with you the surgical options.
This is such an excellent question, I get asked this all the time in my clinic. Kybella gives more predictable and contoured results in my opinion. CoolMini can be an option, but the handpiece limits the amount of contouring that you can do. Comparing apples to apples, these are both non-surgical, noninvasive options for neck rejuvenation with the overall advantage going to Kybella.