What are the pros and cons of Kybella vs. CoolMini?

Both only recently received FDA approval.  It maybe too soon to say which one is better.Both require multiple treatments, Coolmini 2 for a small neck but up to 4 for larger necks.Kybella requires 2 to 5 treatments.Both only have FDA approval for sub mental (under chin) fat and not jowl and jaw line contouring.Although both are non surgical, there can be some swelling and few days worth of downtime with both.Expect up to a 25% in fat reduction in both.  Results are not as good as Smart Lipo.There is no skin tightening.   Both are not ideal for those with significant skin laxity.This can be overcome with non surgical skin tightening treatments for those who want to avoid any and all surgery such as ultrasound (Ultherapy), external radiofrequency (Theramge) or focused radiofrequency (Endymed).I offer patients all the above treatment options but if they are open to laser assisted liposuction, such as Laser Lift or Smart Lipo, this becomes the preferred modality as only one treatment is required, there is only 48 hours of downtime, results are superior, plus the jaw line can be contoured, and skin tightening is accomplished with one treatment modality.  Cost maybe a little more however.Ran Y. Rubinstein, MD
200 Stony Brook Court, Newburgh, New York
Board Certified Facial Plastic Surgeon (ABFPRS)Fellow American Society forLaser Medicine & Surgery (ASLMS)
Clinical Professor New York Presbyterian Hospital
National Education Faculty (physician trainer) for:
Allergan (Botox, Juvederm, Voluma), Galderma
(Scultpra, Restylane, Silk), Cynosure (Cellulaze, Precision Laser Lift)
& Solta (Fraxel, Thermage)Zeltiq( CoolSculpting)

I prefer Kybella because I have much more experience with this product. I have also been very impressed with the results and little downtime or side effects. make sure you do your home work and research both.

Fantastic question! Good to know all of your options.There are multiple factors that go into answering this question...If there is a lot of fat, liposuction is your best bet. This can be done in-office under local anesthesia.If surgery is not something you are comfortable with, Coolsculpting would be your best bet financially... as long as the Coolsculpting applicator fits and you are okay with more time to see full results (than liposuction). If your jaw is too small or the amount of fat too little, the CoolMini may not fit.Lastly, if you have a small amount of fat and the CoolMini applicator doesn't fit your face, I would go with Kybella. There is a significant recovery period with Kybella and the product is not cheap. That is why I reserve it for people with a small amount of submental fat.All three will give you some skin tightening.My best,Dr. Nazarian@drsheilanazarian on Instagram

Thank you for this excellent question.  I am excited that we have both on the market now and I expect many patients using one or both treatment modalities.  The Coolsculpting mini will get a broad reduction of the submental fat but has a little more difficult to customize the procedure as there is only one applicator size.  Kybella allow for a customized treatment for every patient based on their physical exam.  I would visit a plastic surgery a practice that offer both of these and who can also discuss with you the surgical options.

 This is such an excellent question, I get asked this all the time in my clinic. Kybella gives more predictable and contoured results in my opinion. CoolMini can be an option, but the handpiece limits the amount of contouring that you can do. Comparing apples to apples, these are both non-surgical, noninvasive options  for neck rejuvenation with the  overall advantage going to Kybella. 

Please see my video on cosmetic surgery times website.  Both need multiple treamtents and take months to see the results.  Kybella can contour the neck and coolmini cant (applicator only fits certain sizes.  Liposuction with or without thermiRF still gives the best results in my hands with very little downtime.  Best, Dr. Emer.

Both are FDA approved for treating sub-mental fat under the chin and both work. Each also requires about 2-4 treatments so it is really about personal preference. 

Both Kybella and CoolMini are non-surgical treatments used to correct a double chin, and both require multiple treatments. Kybella pros: Works well for smaller pockets of fat; is customizable; is very effective. Kybella cons: Requires injections, and numbness is more common than with CoolMini. CoolMini pros: Is effective on larger pockets of fat; CoolMini cons: Side effects may include numbness, swelling and redness

Kybella and CoolMini are both FDA-approved and are effective in reducing double chins with no down-time. However, they do not address excess skin. Kybella is an injectable treatment that can be tailored to each patient’s unique anatomy. It is great for smaller pockets of fat. It tends to have a higher incidence of numbness and slight bruising, but it’s only temporary. CoolMini freezes fat cells and is useful for treating larger double chins. Its side effects include temporary numbness, swelling and redness. Both Kybella and CoolMini require more then one treatment. A qualified professional can help you sort out the options. 

Both Kybella and CoolMini are treatments that reduce the size of a double chin. Kybella is better for reducing smaller amounts of fat in the chin/neck, and Coolsculpting is a better choice for larger amounts of fat in that area. The treatments can be very effective when used together, too. Coolsculpting can be used first to reduce the fat by freezing the large section of fat under the chin (which the body then eliminates), and then Kybella can then be used to contour the area for a more refined look. Kybella has more swelling and bruising than Coolsculpting. Numbness is also more common with Kybella.  I offer both treatments at my practice so that we can customize and fine tune the treatment combinations to get the absolute best result for our patients. Regardless of which one you choose, both Kybella and CoolMini require more than one treatment.