How Long Will Unreconstituted Botox Last with a Fridge Breakdown?

Doctor Answers 4

Very interesting question...

of course when a refrigerator breaks down, the temperature only slowly returns to room if the door is closed that can take a long time...the only official information on storage of unreconstituted botox is from Allergan...stability studies show the product will be fully effective for 5 days at 86 degrees Fahrenheit...hope this is helpful

Las Vegas Dermatologist
4.6 out of 5 stars 9 reviews

Botox vials are kept in a freezer until mixed and then kept in a refrigerator

As the company received FDA approval for the Botox to be stored as per its insert, there is no data provided to physicians as to how long the Botox powder can remain safe and effective should the power to the refrigerator be cut off.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 37 reviews

Unreconstituted Botox Last with a Fridge Breakdown

With a fridge breakdown of a prolonged nature, then it is not worthwhile to risk using it. Contact the Allergan representative to determine any possibilities of replacing the vial.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.5 out of 5 stars 39 reviews

Up to 36 months, possibly longer.

BOTOX cosmetic is FDA approved for long term storage in a refrigerator (2 to 8 degrees C) when unreconstituted.  As a practical matter, this is a period of time that generally exceeds the actual expiration date on the vial.  This means that while it is possible the unreconstituted BOTOX could be stored in a refrigerator for this long, it should never be used clincally if it is past its expiration date.  I my office, we only hold a 6 week supply of product because of storage considerations.  Once reconstituted, Allergan recommend that the product be used within 4 hours.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.