How Long Does Pain Last After Juvederm Injections?

I had 1cc of juvederm divided evenly to my smile lines 13 days ago. The inital pain was fine but now I still have discomfort. Is this normal?

Doctor Answers 17

Prolonged pain after filler injections may indicate infection

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Prolonged pain after filler injections may indicate infection. Usually this will be accompanied by redness, swelling, and tenderness to touch. In any case see the physician who did the injection for evaluation.

Chicago Dermatologist

Juviderm should not still be hurting

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I have never seen a patient have pain after Juviderm last past a couple of days, and most of the time they are without pain the next day.  You should be seen by the person injected you to make sure you do not have an infection or hematoma.

Pain 13 days after Juvederm for Smile Lines

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It is very unusual to still have discomfort almost two weeks after your Juvederm placement.  Most Juvederm injections now are very comfortable especially with the addition of anesthetic to the Juvederm.  I agree with the other reviewers that you need to see your practitioner to make sure you are not developing a possible infection or other complication especially if there is an ulceration in the skin.



Dr. Liu

Grace Liu, MD
Newport Beach Dermatologic Surgeon
4.9 out of 5 stars 52 reviews

Pain after Juvederm injection

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To answer your question, most patients have very little discomfort following Juvederm injections...especially this far out.  I would definitely go back and see your injectionist to make sure that something else isn't going on.

I hope that helps!

Pain after Juvederm Injection

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Thanks for the question.

13 days out from your Juvederm injection, you should not be experiencing any pain or discomfort. I recommend you follow up with your clinician for an evaluation.


Glenn Vallecillos, M.D., F.A.C.S. 

Glenn Vallecillos, MD, FACS
Beverly Hills Plastic Surgeon
4.9 out of 5 stars 30 reviews

Pain after Juvederm injections

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The new Juvederm XC actually has Lidocaine incorporated into the new folrmula. This improvement, plus a topical anesthetic or a dental block given by the physician should allow for only minimal pain during the treatment.  The discomfort that sometimes comes after the injections should only last a couple of day. I would recommend returning to your physician so he can rule out other complications that can occur.  I hope this helps.

Kindest regards

Neil J. Zemmel

Pain after Hyaluronic acid injection

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After 13 days there should be no pain. You should see your dermatologist to check if an infection has developed.

Robert Kasten, MD
Mainz Dermatologic Surgeon

Juvederm Injections: Minimize the discomfort with the XC product

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Juvederm is a hyaluronic acid based filler that can be utilized for smile lines and other areas of the face. Juvederm has too lines: Ultra and Ultra plus which vary on the amount of cross linking. Allergan just recently released Juvederm with powdered lidocaine in it called Juvederm XC. This is a wonderful product and obviates the need for lower facial dental blocks. I inject the smile lines with topical anesthetic and ice and it is very comfortable. The discomfort you are experiencing currently, is likely from persistent swelling and possible bruising. This can persist for over 2 weeks. You can try cool compresses to the area daily, but I would return for a check up from your physician.

Andrew P. Trussler, MD
Austin Plastic Surgeon
4.9 out of 5 stars 52 reviews

Juvederm or Restylane for smile folds

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the hyaluronic acids can hurt when injected but both companies, that produce Restlane and Juvederm, have added anesthetic to their products. It may hurt a litte during the procedure but it shouldn't hurt afterwards. Maybe it might be a little hard to smile sometimes right after the filler is injected because of the new pressure, but that is temporary and shouldn't hurt. You should see your doctor to make sure there is no infection, which is very rare with these injections.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 39 reviews


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You should not have any pain after the intial swelling.

Now 13 days later i would be concerned about infection. See your physician immediately

Samir Shureih, MD
Baltimore Plastic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.