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Thank you for your question. The frown lines between the brows can be address two different ways:1) Botox or Dysport can be used to soften the deepening of the frown lines when making a frown expression. The treatment may even soften the lines that are present at rest. The effects typically last 3-4 months depending on the dose.2) Restylane or Juvederm can be used to soften the frown lines that are present even when you don't make an expression. This can last for a year or more when used in conjuction with Botox.For someone who has concerns with both the static lines (without expression) and the dynamic lines (with expression), then using both products would work well together. I often find that patients who return after a Botox or Dysport treatment in the frown areas complaining it didn't work, is due to the confusion between the static and dynamic frown lines. They continue to see the static lines even though the dynamic lines have softened considerably.
Both Dysport and Botox can last up to four months. Some people maintain their lack of wrinkling after the Dysport or botox wears off by retraining themselves not to make the grimace. Fillers are usually not used in the frown lines, but hyaluronic acid fillers such as Restylane and Juvederm are safer to use in this location than Radiesse, Sculptra or Fat. Restylane and Juvederm can last a year but fillers in this area must be cautiously used. They are used more often in the cheeks for volume, and the smile folds, and on and off label in the lips. Duration is often 10 to 14 months although patients can see it starting to wear off gradually, sooner.
For discussion, I assume you mean perioral lines. I personal do not like BOTOX for this area. I think fillers are the way to go and Perlane is a fantastic filler for these types of issues. Treatment will easily last over a year.
It generally takes 3 to 5 days for Botox to work. Some individuals can take up to 14 days. For most patients botox should be about 80% effective at 120 days. Most patients report that it lasts up to 4 to 5 months. There are many variables involved including the number of units injected, The location for the injections and The technical skill of the injector. If you are not getting these types of results you may want to go to another provider. Some people just metabolize the product faster than others. I would not recommend fillers in the glabellar area there are reports of blindness and necrosis in this zone.
In our experience, Botox lasts for three to four months on average. This will not be impacted by adding filler nor will Botox affect filler duration.