Most patients are fine the next day and many even the night of the procedure, but don't plan treatment if having a bruise will ruin your holiday and you don't have a week to week and a half of time before your trip. It is rare that patients bruise much, but certain filler treatments are deeper and use wider needles and do have a higher chance of bruising. Avoid blood thinners such as alcohol, Motrin (Advil, Ibuprofen), Aleve, and other non-steroidal antiinflammatory agents, Aspirin, vitamin E, fish oil, and other supplements such as garlic, ginger, ginko biloba and ginseng. If you take a prescribed blood thinner such as Coumadin (warfarin) or Pradaxa you may bruise more than normal but don't discontinue those medications on your own.