Hi Pachuko123, thank you for your post. No, a laser treatment like Laser Genesis should not impact any dermal fillers that you may have, particularly hyaluronic acid fillers like Restylane. Hyaluronic acid is a substance that naturally occurs within the body, and laser treatments are not designed to affect it. In fact, most laser treatments do not penetrate the skin deeply enough to reach and interfere with any injectable dermal fillers. Talk to your Laser Genesis provider before your treatment, however, to make sure they are aware that you have dermal fillers. They may have certain techniques they would prefer to use depending on the types of fillers you currently have. Best of luck!