Has anyone tried to use Latisse to diminish the fat bulging in the undereye area? Are there potential negative side effects?

Question

It appears that one of the documented side effects of bimatoprost (the Latisse ingredient) is fat loss. Allergan is doing clinical trials for XAF5, supposedly a new cream that will be intended for such a purpose. Has anyone tried using Latisse in the under eye area to reduce the fat bulging? Are there any potential negative side effects and if so, would those be reversible once stopping? Of course, assuming it works (a big IF) there may be an issue with the stretched skin once the fat is gone... Thanks!

Jason Emer, MD · Answer

No, this is unlikely to give improvement. A combination approach will give the most improvement. Fillers, lasers, and microneedling/PRP can improve under the eyes. My patients try to get non surgical treatments to avoid surgery. We use PRP and stem cells there often. I suggest consulting with an expert to develop a treatment plan best suited for your short and long term goals. Best, Dr. Emer

Georgios Ziakas, MD, FACS · Answer

Latisse does not have FDA approval for topical fat loss; any such use will be "off label". There are safer options to treat the area.

Emerico Csepanyi, MD · Answer

Latisse should only be used as it is clinically indicated- for use on the upper lash line to achieve longer, fuller, darker lashes as Latisse affects the growth stage of hair follicles. If you have concerns of fat pockets in your orbital area, there are many other treatments available to address those concerns ranging from derma fillers, fat excisions, lasers, etc.

Has anyone tried to use Latisse to diminish the fat bulging in the undereye area? Are there potential negative side effects?

Answers (3)