Can Juvederm Ultra 3 Be Injected into the Glabella Lines?

Doctor Answers 12

Fillers in Glabella Lines

Botox is the first like of defense in our office for this area.  We usually have the patient come back in 10 days to evaluate the result.  If the lines are very deep and have been there for a long time we might consider a filler.  One must be very careful when this is done as there are, (fortunately), rare but possible complications. 

Las Vegas Plastic Surgeon
4.6 out of 5 stars 17 reviews

Two Pronged Approach.

The lines that develop in the glabellar region are caused by the corrugator facial muscles. These muscles are ideal for treating with Botox. However, if the lines are significantly deep enough, using a filler like Juvederm works quite well.

Leslie H. Stevens, MD
Beverly Hills Plastic Surgeon
4.2 out of 5 stars 10 reviews

Not in US yet

This product has not been approved for use in the US. But we do have Juvederm Ultra XC or Juvederm Ultra Plus XC.

Paul Vitenas, Jr., MD
Houston Plastic Surgeon
4.8 out of 5 stars 109 reviews

Yes, Juvederm works very well in glabellar lines.

Juvederm works well with or without Botox in the glabellar lines.  A skilled dermatologist or plastic surgeon understands how to safely perform these filler injecitions.

Mark Taylor, MD
Salt Lake City Dermatologic Surgeon
4.2 out of 5 stars 18 reviews

Fillers in Glabellar Creases...

Having a filler injected in the Glabellar creases is doable  however, it is not FDA approved.  It is done often if the creases are deep to help fill, as an "off label" use.  I always recommend Botox injections on the same visit for best results and to help relax the muscles (the corrugators) that cause the verticle wrinkles. 

Hope this helps.

Dr. Grant Stevens 

Grant Stevens, MD
Los Angeles Plastic Surgeon
4.7 out of 5 stars 147 reviews

Juvederm in the Glabella

Glabellar lines are caused by dermal atrophy from hyperactive muscles in this region.  The best treatment is a combination of Botox and Juvederm for deep lines.  You should first have Botox injected and observe the result for 2 weeks.  If they lines do no completely resolve, then consider having Juvederm Ultra injected under the lines to help soften their appearance.


Good luck.

David Shafer, MD
New York Plastic Surgeon
4.9 out of 5 stars 77 reviews

IMHO fillers should not be injected into the glabella

There are reported cases where fillers, injected into the Glabella, have pinched off the vein traveling in the glabella.  This results in skin slough and scar formation in the center, of the forehead, the size of a quarter.  Best, IMO, to use Botox in the Glabella for this reason.

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.6 out of 5 stars 25 reviews

Fillers for glabellar frown lines

I have abandoned fillers in the glabellar lines after seeing two patients complicated by intravascular embolization/occlusion/ischemia.  The complication is extremely rare, but if you do enough injections, it happens.  I prefer Botox for this area.

Randy Wong, MD
Honolulu Plastic Surgeon
4.8 out of 5 stars 36 reviews

JuveDerm can certainly help glabellar lines.

In the US, we don't have JuveDerm 3 but rather similar products of JuveDerm Ultra and JuveDerm Ultra Plus.  The data shows that the combination of Botox plus filler works better and longer than filler alone (study by Carruthers in Dermtologic Surgery with 18 weeks of Restylane durability in the glabella vs. 32 weeks of durability if Botox was used to pre-treat the area).  So, Botox or Dysport can be very helpful if used first to reduced the movement of the area, and then filler placed about a week later. The filler than doesn;t have the muscles working across it, so work better. The important caveat is that the glabella has blood vessels (supratrochlear artery and dorsal nasal artery) that could be compromised with filler injections, so it is imperative that fillers be used very carefully. Use of a hyaluronic filler is recommended, as the enzyme hyaluronidase is then available to potentially be of assistance in the case of vascular compromise.  For safety purposes, use of low filler volumes and considering a few treatment sessions with a hyaluronic filler is commonly recommended.

Joel L. Cohen, MD
Greenwood Village Dermatologic Surgeon
4.6 out of 5 stars 11 reviews

Juvederm in glabella

Juvederm can be injected in the glabella lines but I would recommend starting with Botox first.  Botox will help soften the lines and prevent new ones from forming.  I would recommend going to a doctor - facial plastic surgeon or dermatologist - who is experienced in injectables to perform either procedures - especially if you have Juvederm placed in the area.  If not done correctly, there can be serious complications.   Either way - Botox and Juvederm are both used routinely to correct these areas and I'm sure you will be very pleased with your results.

Dr. Cat Begovic M.D.

Catherine Huang-Begovic, MD, FACS
Beverly Hills Plastic Surgeon
4.9 out of 5 stars 34 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.