Spider veins are small blue or red veins that appear very close to the surface of the skin - they don't typically bulge outward and are much smaller than varicose veins. The best way to treat spider veins is sclerotherapy (injection of the veins). External laser is sometimes used, as is VeinGogh, but most vein experts agree that sclerotherapy is best. VenaSeal is a procedure that is used to treat reflux (backwards flow) in veins beneath the skin surface that typically cause varicose veins. VenaSeal might be used in some patients to treat reflux, if present, in someone who might eventually have their spider veins treated, but VenaSeal is not a treatment for spider veins per se. Sclerotherapy, by the way, is considerably less expensive than VenaSeal.